Web1 de out. de 2024 · Tumor quiescence: elevating SOX2 in diverse tumor cell types downregulates a broad spectrum of the cell cycle machinery and inhibits tumor growth. 1 Coronavirus: Find the latest articles and preprints Web30 de jul. de 2009 · The expression of TrkB and GRPR was confirmed by immunohistochemistry and mRNA for both BDNF and GRPR was detected by reverse transcriptase polymerase chain reaction in Daoy, D283, and ONS76 cells. Treatment with BDNF significantly inhibited the viability of Daoy and D283, but not ONS76 cells, …
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Web13 de ago. de 2011 · Current chemotherapeutics induce autophagy in pediatric brain tumor cell lines. AT/RT (BT-12, BT-16) and medulloblastoma (DAOY, ONS76) cells were treated with starvation stress, CCNU or cisplatin for 8 h at the estimated LD50 based on previous MTS assays (data not shown) in the presence or absence of lysosomal protease … raypak heater anode
BDNF and PDE4, but not the GRPR, regulate viability of human ...
Web13 de out. de 2014 · MST-312 induces telomere shortening and reduces cell proliferation in brain tumour cells. (A) Total genomic DNA prepared from MO59K, KNS60 and ONS76 cells treated with 0.5 μM MST-312 for indicated number of days was assessed for telomere length using TRF assay.(B-D) Cell proliferation capacity in 0.5 μM MST-312 treated brain … Web30 de jul. de 2009 · Cell viability was dose-dependently inhibited in D283 and ONS76 cells by rolipram at 100 µM (Ps < 0.001 compared to control cells; Fig. 4a). Rolipram inhibited the viability of Daoy cells also when combined with GRP ( P s < 0.001, comparisons between cells treated with rolipram alone or rolipram plus GRP compared to control cells; Fig. 4b ). Web12 de abr. de 2024 · ONS76 cells were in common with the DEGs when SOX2 was elevated in i-SOX2-ONS76. cells (Figure 4 D), demonstrating that SOX2 elevation significantly affected the expression. raypak heater 406a parts