Circular RNA (or circRNA) is a type of single-stranded RNA which, unlike linear RNA, forms a covalently closed continuous loop. In circular RNA, the 3' and 5' ends normally present in an RNA molecule have been joined together. This feature confers numerous properties to circular RNA, many of which have only recently been identified. Many types of circular RNA arise from otherwise protein-coding genes. Some circular RNA has … WebMay 10, 2024 · Flagship Pioneering has launched Laronde to create a new kind of RNA therapy that is circular instead of linear—one it calls endless RNA, or eRNA for short. Flagship has committed $50 million to …
Flagship’s next genetic meds startup has $50M for transfer at a ...
WebAug 30, 2024 · Laronde, which, fittingly, is named after the French word for round, says the key advantage of eRNA is its circular shape. Often, linear RNA doesn't last very long … WebNov 9, 2024 · Flagship Pioneering, the venture capital firm that formed mRNA company Moderna, has been working on a new startup that tackles an overlooked form of RNA. … chishiya personality type
EP2996697A4 - Intracellular translation of circular rna - Google
WebJun 2, 2024 · Circular RNAs (circRNA) is a class of natural (biogenic) or synthetic closed RNA without 5' or 3' ends. Meanwhile, their unique covalently-closed structures of circRNA prevent RNA degradation by exonucleases, thereby empowering them with high pharmaceutical stability and biostability relative to cur … WebMay 10, 2024 · CAMBRIDGE, Mass., May 10, 2024 /PRNewswire/ -- Flagship Pioneering today unveiled Laronde, a platform company developing Endless RNA™ (eRNA), a novel, engineered form of RNA … WebMay 10, 2024 · Flagship Pioneering, the company-creating venture fund that launched Moderna Inc. in 2012, is betting $50 million on a new twist in RNA-focused development at Laronde Inc. Leveraging its explorations … chishiya de alice in borderland