WebMigration of differentiated cells contributes to repair. To investigate mechanisms of epithelial repair, we established a platform to study by time-lapse microscopy the repair of 1 mm wide wounds by tracking fluorescently marked epithelial cell nuclei (fusion protein of histone H2B with green fluorescent protein (GFP) driven by the keratin 14 promoter (K14-H2BGFP … WebCellular processes, such as transcription, DNA replication, and DNA repair, are regulated by an intimate and self-reinforcing crosstalk and interdependence between histone-modifying complexes and other histone-modifying activities, ... Proteins “A” and “B” serve as hub proteins (schematic 1). An alteration (mutation) that removes one of ...
Tissue-scale coordination of cellular behavior promotes epidermal …
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